Ki Summary

Reaction Details

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Target

2-oxoglutarate receptor 1

Ligand

BDBM50369939

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_151406 (CHEMBL754752)

2000±n/a nM

Citation

Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem44:208-14 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

2-oxoglutarate receptor 1

Name:

2-oxoglutarate receptor 1

Synonyms:

G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15

Type:

PROTEIN

Mol. Mass.:

38385.93

Organism:

Rattus norvegicus

Description:

ChEMBL_151406

Residue:

337

Sequence:

MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVF
KMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSS
ILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNR
SACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKAR
RLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLL
LYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP

BDBM50369939

n/a

Name

BDBM50369939

Synonyms:

CHEMBL609774

Type

Small organic molecule

Emp. Form.

C20H26N6O4

Mol. Mass.

414.4582

SMILES

Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1C2CC3CC(C2)CC1C3 |r,wU:12.19,wD:15.18,13.15,TLB:19:20:22:25.26.24,THB:27:28:22:25.26.24,27:25:22:20.28.29,24:23:20:25.27.26,24:25:20:23.22.29,(17.28,-1.3,;17.3,-2.84,;18.64,-3.59,;18.64,-5.13,;17.3,-5.88,;15.98,-5.13,;14.54,-5.61,;13.66,-4.36,;14.54,-3.12,;15.98,-3.59,;13.52,-6.72,;12.25,-5.92,;11.07,-6.88,;11.6,-8.31,;10.68,-9.71,;13.14,-8.21,;14.19,-9.49,;9.58,-6.53,;9.14,-5.06,;8.52,-7.64,;7.07,-7.22,;5.81,-7.32,;4.51,-8.59,;3.26,-7.7,;1.79,-6.2,;2.3,-4.16,;2.87,-6.18,;4.43,-4.16,;5.81,-6.3,;4.59,-7.55,)|

Structure