Ki Summary

Reaction Details

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Target

2-oxoglutarate receptor 1

Ligand

BDBM50369951

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_151406 (CHEMBL754752)

833±n/a nM

Citation

Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem44:208-14 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

2-oxoglutarate receptor 1

Name:

2-oxoglutarate receptor 1

Synonyms:

G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15

Type:

PROTEIN

Mol. Mass.:

38385.93

Organism:

Rattus norvegicus

Description:

ChEMBL_151406

Residue:

337

Sequence:

MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVF
KMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSS
ILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNR
SACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKAR
RLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLL
LYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP

BDBM50369951

n/a

Name

BDBM50369951

Synonyms:

CHEMBL609179

Type

Small organic molecule

Emp. Form.

C19H24N6O4

Mol. Mass.

400.4317

SMILES

Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC12CC3CC(CC3C1)C2 |r,wU:12.19,wD:15.18,13.15,TLB:21:20:22.23:25,23:24:27:22.21,19:20:22.23:25,THB:21:22:25:20.27.28,23:22:27:24.25.28,(14.56,-1.07,;14.59,-2.62,;15.94,-3.39,;15.94,-4.93,;14.59,-5.72,;13.23,-4.95,;11.77,-5.42,;10.88,-4.16,;11.77,-2.92,;13.23,-3.39,;10.74,-6.56,;9.46,-5.74,;8.24,-6.72,;8.8,-8.16,;7.96,-9.46,;10.34,-8.06,;11.32,-9.25,;6.73,-6.37,;6.28,-4.88,;5.68,-7.47,;4.32,-7.5,;4.11,-8.82,;2.78,-9,;1.83,-9.94,;.64,-9.31,;.99,-8.02,;2.18,-7.81,;3.13,-6.88,;1.9,-6.86,)|

Structure