Ki Summary

Reaction Details

Report a problem with these data

Target

2-oxoglutarate receptor 1

Ligand

BDBM50409303

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_151406 (CHEMBL754752)

55.6±n/a nM

Citation

Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem44:208-14 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

2-oxoglutarate receptor 1

Name:

2-oxoglutarate receptor 1

Synonyms:

G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15

Type:

PROTEIN

Mol. Mass.:

38385.93

Organism:

Rattus norvegicus

Description:

ChEMBL_151406

Residue:

337

Sequence:

MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVF
KMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSS
ILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNR
SACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKAR
RLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLL
LYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP

BDBM50409303

n/a

Name

BDBM50409303

Synonyms:

CHEMBL2092773

Type

Small organic molecule

Emp. Form.

C17H24N6O4

Mol. Mass.

376.4103

SMILES

C[C@H]1CC[C@H](CC1)NC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r,wU:12.18,10.10,4.7,1.0,wD:13.14,15.17,(-5.64,-3.71,;-4.16,-3.95,;-3.13,-2.74,;-1.62,-3.03,;-1.11,-4.47,;-2.11,-5.66,;-3.6,-5.37,;.43,-4.75,;1.43,-3.58,;.87,-2.12,;2.96,-3.86,;4.08,-2.81,;5.43,-3.58,;5.1,-5.07,;6.12,-6.22,;3.57,-5.21,;2.78,-6.54,;6.47,-2.43,;5.54,-1.19,;6.47,.07,;7.92,-.4,;9.27,.35,;9.27,1.88,;10.59,-.4,;10.59,-1.95,;9.27,-2.74,;7.92,-1.95,)|

Structure