| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M5 |
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| Ligand | BDBM50105094 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_139387 (CHEMBL747700) |
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| IC50 | 1910±n/a nM |
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| Citation |  Poulain, R; Horvath, D; Bonnet, B; Eckhoff, C; Chapelain, B; Bodinier, MC; Déprez, B From hit to lead. Analyzing structure-profile relationships. J Med Chem44:3391-401 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M5 |
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| Name: | Muscarinic acetylcholine receptor M5 |
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| Synonyms: | ACM5_HUMAN | CHRM5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60102.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1517990 |
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| Residue: | 532 |
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| Sequence: | MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE
KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL
TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN
YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP
NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
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| BDBM50105094 |
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| n/a |
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| Name | BDBM50105094 |
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| Synonyms: | 1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one | CHEMBL114379 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20ClN3O3 |
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| Mol. Mass. | 385.844 |
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| SMILES | Clc1cc2OCOc2cc1CN1CCC(CC1)n1c2ccccc2[nH]c1=O |
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| Structure | 
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