| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50095893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60684 (CHEMBL675946) |
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| Ki | 4.3±n/a nM |
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| Citation |  Rowley, M; Bristow, LJ; Hutson, PH Current and novel approaches to the drug treatment of schizophrenia. J Med Chem44:477-501 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50095893 |
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| n/a |
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| Name | BDBM50095893 |
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| Synonyms: | 3-{4-[2-(2-Chloro-phenyl)-ethyl]-piperazin-1-yl}-4,5-dihydro-1H-benzo[g]indazole | CHEMBL422314 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN4 |
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| Mol. Mass. | 392.924 |
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| SMILES | Clc1ccccc1CCN1CCN(CC1)c1[nH]nc-2c1CCc1ccccc-21 |
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| Structure | 
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