| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50208788 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_30008 (CHEMBL641299) |
|---|
| Ki | 17±n/a nM |
|---|
| Citation |  Rieger, JM; Brown, ML; Sullivan, GW; Linden, J; Macdonald, TL Design, synthesis, and evaluation of novel A2A adenosine receptor agonists. J Med Chem44:531-9 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 45015.65 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Rat A2A receptors expressed in CHO cells. |
|---|
| Residue: | 410 |
|---|
| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
|
|
|
|---|
| BDBM50208788 |
|---|
| n/a |
|---|
| Name | BDBM50208788 |
|---|
| Synonyms: | (2R,3R,4S,5R)-2-(6-amino-2-phenethoxy-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol | CHEMBL374685 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H21N5O5 |
|---|
| Mol. Mass. | 387.3898 |
|---|
| SMILES | Nc1nc(OCCc2ccccc2)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
|---|
| Structure | 
|
|---|
Search and Browse
