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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM50370001 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_30008 (CHEMBL641299) | ||
| Ki | 6.2±n/a nM | ||
| Citation |  Rieger, JM; Brown, ML; Sullivan, GW; Linden, J; Macdonald, TL Design, synthesis, and evaluation of novel A2A adenosine receptor agonists. J Med Chem44:531-9 (2001) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 45015.65 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Rat A2A receptors expressed in CHO cells. | ||
| Residue: | 410 | ||
| Sequence: |
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| BDBM50370001 | |||
| n/a | |||
| Name | BDBM50370001 | ||
| Synonyms: | CHEMBL608948 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H32N6O6 | ||
| Mol. Mass. | 476.5261 | ||
| SMILES | CCNC(=O)[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)nc(CC3CCC(COC(C)=O)CC3)nc12 |r,wU:5.4,wD:8.8,10.11,(-4.53,-5.43,;-3.37,-4.42,;-1.92,-4.92,;-.76,-3.92,;-1.05,-2.41,;.7,-4.42,;2.66,-3.45,;4.64,-4.42,;3.89,-5.95,;4.73,-7.3,;1.43,-5.95,;.57,-7.3,;4.66,-2.89,;3.76,-1.64,;4.66,-.4,;6.11,-.87,;7.44,-.1,;7.44,1.44,;8.78,-.87,;8.78,-2.41,;10.11,-3.17,;10.11,-4.71,;11.44,-5.47,;11.44,-7.02,;10.1,-7.78,;10.1,-9.32,;11.43,-10.09,;12.77,-9.32,;12.77,-7.78,;14.09,-10.09,;8.78,-7.01,;8.78,-5.48,;7.44,-3.17,;6.11,-2.41,)| | ||
| Structure | 
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