| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50067081 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30024 (CHEMBL641315) |
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| Ki | 3.3±n/a nM |
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| Citation |  van Muijlwijk-Koezen, JE; Timmerman, H; Vollinga, RC; Frijtag von Drabbe Künzel, J; de Groote, M; Visser, S; IJzerman, AP Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem44:749-62 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 45015.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat A2A receptors expressed in CHO cells. |
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| Residue: | 410 |
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| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
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| BDBM50067081 |
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| n/a |
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| Name | BDBM50067081 |
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| Synonyms: | 9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine | 9-Fluoro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine | CGS-15943 | CHEMBL70605 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H8FN5O |
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| Mol. Mass. | 269.2339 |
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| SMILES | Nc1nc2ccc(F)cc2c2nc(nn12)-c1ccco1 |
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| Structure | 
|
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