| Reaction Details |
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 | Report a problem with these data |
| Target | Progesterone receptor |
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| Ligand | BDBM50113778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159546 (CHEMBL765662) |
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| Ki | >10000±n/a nM |
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| Citation |  Morgan, BP; Swick, AG; Hargrove, DM; LaFlamme, JA; Moynihan, MS; Carroll, RS; Martin, KA; Lee, E; Decosta, D; Bordner, J Discovery of potent, nonsteroidal, and highly selective glucocorticoid receptor antagonists. J Med Chem45:2417-24 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Progesterone receptor |
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| Name: | Progesterone receptor |
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| Synonyms: | NR3C3 | Nuclear receptor subfamily 3 group C member 3 | PGR | PR | PRGR_HUMAN | progesterone |
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| Type: | Protein |
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| Mol. Mass.: | 98979.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06401 |
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| Residue: | 933 |
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| Sequence: | MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLF
PRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLA
PSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAA
AHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGK
PRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTV
MDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPD
CAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLG
PPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPC
KAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPP
YLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHN
YLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPV
GVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQ
LGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAP
DLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQ
FEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRA
LSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
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| BDBM50113778 |
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| n/a |
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| Name | BDBM50113778 |
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| Synonyms: | (S)-4a-Benzyl-7-methoxy-4,4a,9,10-tetrahydro-3H-phenanthren-2-one | CHEMBL82307 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22O2 |
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| Mol. Mass. | 318.4089 |
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| SMILES | COc1ccc2c(CCC3=CC(=O)CC[C@]23Cc2ccccc2)c1 |t:9| |
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| Structure | 
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