| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 |
|---|
| Ligand | BDBM17660 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106687 (CHEMBL714668) |
|---|
| Ki | 112000±n/a nM |
|---|
| Citation |  Bertrand, HO; Bessis, AS; Pin, JP; Acher, FC Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity. J Med Chem45:3171-83 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 4 |
|---|
| Name: | Metabotropic glutamate receptor 4 |
|---|
| Synonyms: | GPRC1D | GRM4 | GRM4_HUMAN | Glutamate receptor, metabotropic 4 | MGLUR4 | Metabotropic glutamate receptor 4 | Metabotropic glutamate receptor 4 (mGlu4) | Metabotropic glutamate receptor 4 (mGluR4) | metabotropic glutamate 4 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 101899.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q14833 |
|---|
| Residue: | 912 |
|---|
| Sequence: | MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ
KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA
ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT
KQTYVTYTNHAI
|
|
|
|---|
| BDBM17660 |
|---|
| n/a |
|---|
| Name | BDBM17660 |
|---|
| Synonyms: | (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid | 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid | CHEMBL279956 | Quisqualate | Quisqualate, L | quisqualic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H7N3O5 |
|---|
| Mol. Mass. | 189.1262 |
|---|
| SMILES | N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
