| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
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| Ligand | BDBM50118218 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_149733 (CHEMBL759516) |
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| IC50 | 8800±n/a nM |
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| Citation |  Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem45:4057-93 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 1 |
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| Name: | P2X purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RX1_RAT | P2X1 | P2rx1 | Purinergic receptor | Purinergic, P2X1 | RP-2 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44969.95 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X1 0 RAT::P47824 |
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| Residue: | 399 |
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| Sequence: | MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSD
LISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIVTPQQTQGHCAEN
PEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKIQHPLCPVFNLGYVVRESG
QDFRSLAEKGGVVGITIDWKCDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQN
GTNRRHLFKVFGIHFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGEGEHDPVATSSTLGLQENMRTS
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| BDBM50118218 |
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| n/a |
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| Name | BDBM50118218 |
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| Synonyms: | CHEMBL131271 | Disodium 1-amino-4-[4-(4,6-dichloro-[1,3,5]triazine-2-ylamino)-3-sulfophenylamino]-9,10-dioxo-9,10-di-hydroanthracene-2-sulfonate | MG 40-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H12Cl2N6O8S2 |
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| Mol. Mass. | 635.414 |
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| SMILES | Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Cl)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O |
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| Structure | 
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