Reaction Details |
| Report a problem with these data |
Target | P2X purinoceptor 3 |
---|
Ligand | BDBM85043 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_147403 (CHEMBL884064) |
---|
EC50 | 1700±n/a nM |
---|
Citation | Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem45:4057-93 (2002) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
P2X purinoceptor 3 |
---|
Name: | P2X purinoceptor 3 |
Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa |
Type: | Protein |
Mol. Mass.: | 44292.02 |
Organism: | Homo sapiens (Human) |
Description: | P56373 |
Residue: | 397 |
Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
|
|
|
BDBM85043 |
---|
n/a |
---|
Name | BDBM85043 |
Synonyms: | CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPADS |
Type | Small organic molecule |
Emp. Form. | C14H14N3O12PS2 |
Mol. Mass. | 511.378 |
SMILES | Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O |w:4.3| |
Structure |
|