| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
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| Ligand | BDBM50118228 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_149728 (CHEMBL759511) |
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| IC50 | 210±n/a nM |
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| Citation |  Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem45:4057-93 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 1 |
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| Name: | P2X purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RX1 | P2RX1_HUMAN | P2X1 | Purinergic receptor | Purinergic, P2X |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44992.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purinergic, P2X 0 HUMAN::P51575 |
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| Residue: | 399 |
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| Sequence: | MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESG
QNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVEN
GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
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| BDBM50118228 |
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| n/a |
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| Name | BDBM50118228 |
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| Synonyms: | 5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-1-ylcarbamoyl)-phenyl]-ureido}-benzoylamino)-naphthalene-1-sulfonic acid anion;hexasodium salt | CHEMBL216504 | Urea derivative |
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| Type | Small organic molecule |
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| Emp. Form. | C35H20N4O21S6 |
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| Mol. Mass. | 1024.941 |
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| SMILES | [O-]S(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc4ccc(c5cc(cc(c45)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O |
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| Structure | 
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