| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
|---|
| Ligand | BDBM50118230 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_147742 (CHEMBL756289) |
|---|
| EC50 | 82±n/a nM |
|---|
| Citation |  Jacobson, KA; Jarvis, MF; Williams, M Purine and pyrimidine (P2) receptors as drug targets. J Med Chem45:4057-93 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 12 |
|---|
| Name: | P2Y purinoceptor 12 |
|---|
| Synonyms: | P2Y purinoceptor 12 | P2Y12_RAT | P2ry12 | P2y12 | Purinergic receptor P2Y12 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39068.50 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1454020 |
|---|
| Residue: | 343 |
|---|
| Sequence: | MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIR
SKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISF
LGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITK
CSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRV
NIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLD
PFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM
|
|
|
|---|
| BDBM50118230 |
|---|
| n/a |
|---|
| Name | BDBM50118230 |
|---|
| Synonyms: | 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE | ADPbetaS | CHEMBL335206 | adenosine-5'-O-beta-thiodiphosphate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H15N5O9P2S |
|---|
| Mol. Mass. | 443.267 |
|---|
| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O |
|---|
| Structure | 
|
|---|
Search and Browse
