| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50118497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_210617 (CHEMBL811734) |
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| IC50 | 11000±n/a nM |
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| Citation |  Hernández, AI; Balzarini, J; Karlsson, A; Camarasa, MJ; Pérez-Pérez, MJ Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. J Med Chem45:4254-63 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
|
|
|
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| BDBM50118497 |
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| n/a |
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| Name | BDBM50118497 |
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| Synonyms: | CHEMBL134449 | Heptanoic acid 3-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-propenyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N2O4 |
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| Mol. Mass. | 294.3462 |
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| SMILES | CCCCCCC(=O)O\C=C/Cn1cc(C)c(=O)[nH]c1=O |
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| Structure | 
|
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