| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM1 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_208017 (CHEMBL814146) |
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| IC50 | 26±n/a nM |
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| Citation |  Hernández, AI; Balzarini, J; Karlsson, A; Camarasa, MJ; Pérez-Pérez, MJ Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. J Med Chem45:4254-63 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
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| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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| BDBM1 |
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| n/a |
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| Name | BDBM1 |
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| Synonyms: | dT | thymidine |
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| Type | Nucleoside or nucleotide |
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| Emp. Form. | C10H14N2O5 |
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| Mol. Mass. | 242.2286 |
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| SMILES | Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O |
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| Structure | 
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