| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50108563 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_45269 (CHEMBL658221) |
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| Ki | 65±n/a nM |
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| Citation |  Masereel, B; Rolin, S; Abbate, F; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. J Med Chem45:312-20 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 35152.74 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Bovine isozyme, isolated from lung microsomes |
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| Residue: | 312 |
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| Sequence: | MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAK
TQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSR
AMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQ
PLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQK
PIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLA
PVLACLTVGFLR
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| BDBM50108563 |
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| n/a |
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| Name | BDBM50108563 |
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| Synonyms: | Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-amide | CHEMBL108971 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H18N4O3S2 |
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| Mol. Mass. | 342.437 |
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| SMILES | NS(=O)(=O)c1nnc(NC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)s1 |TLB:18:17:20:12.13.14,18:13:20:19.17.16| |
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| Structure | 
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