| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50007567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62766 (CHEMBL676293) |
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| Ki | 21±n/a nM |
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| Citation |  Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies. J Med Chem45:344-59 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
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| Type: | Protein |
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| Mol. Mass.: | 49540.58 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P19020 |
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| Residue: | 446 |
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| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
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| BDBM50007567 |
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| n/a |
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| Name | BDBM50007567 |
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| Synonyms: | 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine | CHEMBL64875 | OCTOCLOTHEPIN-R |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClN2S |
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| Mol. Mass. | 344.901 |
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| SMILES | CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 |
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| Structure | 
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