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TargetD(2) dopamine receptor
LigandBDBM50099273
Substrate/Competitorn/a
Meas. Tech.ChEMBL_87873 (CHEMBL697295)
Ki>1500±n/a nM
Citation Fletcher, SRBurkamp, FBlurton, PCheng, SKClarkson, RO'Connor, DSpinks, DTudge, Mvan Niel, MBPatel, SChapman, KMarwood, RShepheard, SBentley, GCook, GPBristow, LJCastro, JLHutson, PHMacLeod, AM 4-(Phenylsulfonyl)piperidines: novel, selective, and bioavailable 5-HT(2A) receptor antagonists. J Med Chem45:492-503 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:D(2) dopamine receptor
Synonyms:D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM50099273
n/a
NameBDBM50099273
Synonyms:6-Fluoro-3-(4-fluoro-piperidin-3-yl)-2-phenyl-1H-indole | CHEMBL288856
TypeSmall organic molecule
Emp. Form.C19H18F2N2
Mol. Mass.312.3564
SMILESF[C@@H]1CCNCC1c1c([nH]c2cc(F)ccc12)-c1ccccc1
Structure
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