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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50121521
Substrate/Competitorn/a
Meas. Tech.ChEMBL_158026
Ki 0.910000±n/a nM
Kd 48±n/a nM
KON 1850000 M-1s-1
Citation Markgren POSchaal WHämäläinen MKarlén AHallberg ASamuelsson BDanielson UH Relationships between structure and interaction kinetics for HIV-1 protease inhibitors. J Med Chem 45:5430-9 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50121521
n/a
NameBDBM50121521
Synonyms:2-({2,5-Bis-benzyloxy-5-[(1-carboxy-2-methyl-butyl)-methyl-carbamoyl]-3,4-dihydroxy-pentanoyl}-methyl-amino)-3-methyl-pentanoic acid | CHEMBL149472
TypeSmall organic molecule
Emp. Form.C34H48N2O10
Mol. Mass.644.7523
SMILESCCC(C)C(N(C)C(=O)[C@H](OCc1ccccc1)[C@H](O)[C@@H](O)[C@@H](OCc1ccccc1)C(=O)N(C)C(C(C)CC)C(O)=O)C(O)=O
Structure
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