| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50121524 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158026 (CHEMBL768619) |
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| Ki | >5000±n/a nM |
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| Citation |  Markgren, PO; Schaal, W; Hämäläinen, M; Karlén, A; Hallberg, A; Samuelsson, B; Danielson, UH Relationships between structure and interaction kinetics for HIV-1 protease inhibitors. J Med Chem45:5430-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
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| BDBM50121524 |
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| n/a |
|---|
| Name | BDBM50121524 |
|---|
| Synonyms: | (2R,3R,4R,5R)-2,5-Bis-benzyloxy-3,4-dihydroxy-hexanedioic acid bis-[(pyridin-2-ylmethyl)-amide] | 2,5-Bis-benzyloxy-3,4-dihydroxy-hexanedioic acid bis-[(pyridin-2-ylmethyl)-amide] | CHEMBL124065 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H34N4O6 |
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| Mol. Mass. | 570.6356 |
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| SMILES | O[C@H]([C@@H](O)[C@@H](OCc1ccccc1)C(=O)NCc1ccccn1)[C@@H](OCc1ccccc1)C(=O)NCc1ccccn1 |
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| Structure | 
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