| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158026 (CHEMBL768619) |
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| Ki | 920±n/a nM |
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| Citation |  Markgren, PO; Schaal, W; Hämäläinen, M; Karlén, A; Hallberg, A; Samuelsson, B; Danielson, UH Relationships between structure and interaction kinetics for HIV-1 protease inhibitors. J Med Chem45:5430-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM329 |
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| n/a |
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| Name | BDBM329 |
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| Synonyms: | (3R,4S,5S,6R)-3,6-Bis(phenoxymethyl)-2,7-bis[4-(2-thienyl)benzyl]-4,5-dihydroxy-1,2,7-thiadiazepine 1,1-Dioxide | (3R,4S,5S,6R)-4,5-dihydroxy-3,6-bis(phenoxymethyl)-2,7-bis({[4-(thiophen-2-yl)phenyl]methyl})-1,2,7-thiadiazepane-1,1-dione | CHEMBL345997 | Cyclic Sulfamide deriv. 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H38N2O6S3 |
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| Mol. Mass. | 738.935 |
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| SMILES | O[C@@H]1[C@@H](O)[C@@H](COc2ccccc2)N(Cc2ccc(cc2)-c2cccs2)S(=O)(=O)N(Cc2ccc(cc2)-c2cccs2)[C@@H]1COc1ccccc1 |r| |
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| Structure | 
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