| Reaction Details |
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 | Report a problem with these data |
| Target | Disintegrin and metalloproteinase domain-containing protein 9 |
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| Ligand | BDBM50109637 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_63593 (CHEMBL675240) |
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| IC50 | 430±n/a nM |
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| Citation |  Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H New type of metalloproteinase inhibitor: design and synthesis of new phosphonamide-based hydroxamic acids. J Med Chem45:919-29 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Disintegrin and metalloproteinase domain-containing protein 9 |
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| Name: | Disintegrin and metalloproteinase domain-containing protein 9 |
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| Synonyms: | ADAM9 | ADAM9_HUMAN | Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) | KIAA0021 | MCMP | MDC9 | MLTNG |
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| Type: | Enzyme |
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| Mol. Mass.: | 90567.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13443 |
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| Residue: | 819 |
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| Sequence: | MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPR
PYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYV
EGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNK
DIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMI
LLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNK
LVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSEC
DVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCF
IEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKC
WGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNK
NCHCENGWAPPNCETKGYGGSVDSGPTYNEMNTALRDGLLVFFFLIVPLIVCAIFIFIKR
DQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPREVPIYANRFAVPTYAA
KQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT
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| BDBM50109637 |
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| n/a |
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| Name | BDBM50109637 |
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| Synonyms: | 4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydroxycarbamoyl-piperazine-1-carboxylic acid benzyl ester | CHEMBL173235 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N3O7P |
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| Mol. Mass. | 477.4474 |
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| SMILES | CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 |
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| Structure | 
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