| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
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| Ligand | BDBM50118229 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_149727 (CHEMBL759510) |
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| IC50 | 1150±n/a nM |
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| Citation |  Raboisson, P; Baurand, A; Cazenave, JP; Gachet, C; Retat, M; Spiess, B; Bourguignon, JJ Novel antagonists acting at the P2Y(1) purinergic receptor: synthesis and conformational analysis using potentiometric and nuclear magnetic resonance titration techniques. J Med Chem45:962-72 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 1 |
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| Name: | P2X purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RX1 | P2RX1_HUMAN | P2X1 | Purinergic receptor | Purinergic, P2X |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44992.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purinergic, P2X 0 HUMAN::P51575 |
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| Residue: | 399 |
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| Sequence: | MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESG
QNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVEN
GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
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| BDBM50118229 |
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| n/a |
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| Name | BDBM50118229 |
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| Synonyms: | CHEMBL129841 | MRS 2179 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17N5O9P2 |
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| Mol. Mass. | 425.2283 |
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| SMILES | CNc1ncnc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O1 |
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| Structure | 
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