| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Ligand | BDBM50110681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197988 (CHEMBL799490) |
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| IC50 | 0.14±n/a nM |
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| Citation |  McCluskey, A; Sim, AT; Sakoff, JA Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies. J Med Chem45:1151-75 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Name: | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
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| Synonyms: | PP1G_HUMAN | PPP1CC | Serine/threonine protein phosphatase PP1-gamma catalytic subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36983.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_473188 |
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| Residue: | 323 |
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| Sequence: | MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
KKKPNATRPVTPPRGMITKQAKK
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| BDBM50110681 |
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| n/a |
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| Name | BDBM50110681 |
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| Synonyms: | CHEMBL430266 | Calyculin-A |
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| Type | Small organic molecule |
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| Emp. Form. | C50H81N4O15P |
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| Mol. Mass. | 1009.1697 |
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| SMILES | COC[C@@H]([C@H](O)[C@H](O)C(=O)NCC[C@H](C)c1nc(\C=C\C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)\C=C(/C)\C(\C)=C\C=C\C(\C)=C/C#N)OC)[C@H](OP(O)(O)=O)C3(C)C)co1)N(C)C |r| |
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| Structure | 
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