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TargetAmine oxidase [flavin-containing] B
LigandBDBM50110715
Substrate/Competitorn/a
Meas. Tech.ChEMBL_123738 (CHEMBL728381)
Ki 220±n/a nM
Citation Mai, A; Artico, M; Esposito, M; Sbardella, G; Massa, S; Befani, O; Turini, P; Giovannini, V; Mondovì, B 3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A. J Med Chem45:1180-3 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] B
Name:Amine oxidase [flavin-containing] B
Synonyms:AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B
Type:PROTEIN
Mol. Mass.:58428.94
Organism:Bos taurus
Description:ChEMBL_1501478
Residue:520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWR
TMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEV
SALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQ
TGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVY
YKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEER
LKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTT
FLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
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  Blast E-value cutoff:
BDBM50110715
n/a
NameBDBM50110715
Synonyms:5-Methoxymethyl-3-[4-(4,4,4-trifluoro-3-hydroxy-butoxy)-phenyl]-oxazolidin-2-one | CHEMBL18101
TypeSmall organic molecule
Emp. Form.C15H18F3NO5
Mol. Mass.349.3023
SMILESCOC[C@@H]1CN(C(=O)O1)c1ccc(OCC[C@H](O)C(F)(F)F)cc1
Structure
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