| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50122648 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38615 (CHEMBL857081) |
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| IC50 | 6457±n/a nM |
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| Citation |  Tanaka, N; Tamai, T; Mukaiyama, H; Hirabayashi, A; Muranaka, H; Ishikawa, T; Kobayashi, J; Akahane, S; Akahane, M Relationship between stereochemistry and the beta3-adrenoceptor agonistic activity of 4'-hydroxynorephedrine derivative as an agent for treatment of frequent urination and urinary incontinence. J Med Chem46:105-12 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2_CANLF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46593.67 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_56504 |
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| Residue: | 415 |
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| Sequence: | MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIAR
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRF
HAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNS
RSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
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| BDBM50122648 |
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| n/a |
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| Name | BDBM50122648 |
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| Synonyms: | (alphaS,betaR)(2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid | CHEMBL13560 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22ClNO5 |
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| Mol. Mass. | 379.835 |
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| SMILES | C[C@@H](NCCc1ccc(OCC(O)=O)c(Cl)c1)[C@@H](O)c1ccc(O)cc1 |
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| Structure | 
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