Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50122529 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_145593 (CHEMBL749738) | ||
IC50 | >10000±n/a nM | ||
Citation | Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
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BDBM50122529 | |||
n/a | |||
Name | BDBM50122529 | ||
Synonyms: | 17-cyclopropylmethyl-4,5,12,13-tetramethoxy-16-methyl-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaene | ||
Type | Small organic molecule | ||
Emp. Form. | C25H33NO4 | ||
Mol. Mass. | 411.5338 | ||
SMILES | COC1=C(OC)C=C2[C@@H](C1)[C@@H]1Cc3cc(OC)c(OC)cc3[C@@H]2[C@@H](C)N1CC1CC1 |wU:22.24,10.28,8.8,23.26,c:2,6,TLB:24:23:7.8:21.12.11,20:21:7.8:25.23,THB:9:8:25.23:21.12.11,26:25:7.8:21.12.11,13:12:7.8:25.23,(10.65,1.58,;9.32,2.35,;7.98,1.58,;6.63,2.35,;6.63,3.89,;5.3,4.66,;5.3,1.58,;5.3,.04,;6.63,-.73,;7.98,.04,;6.86,-4.6,;5.3,-4.6,;3.97,-3.83,;2.64,-4.6,;1.31,-3.83,;-.02,-4.6,;-1.35,-3.83,;1.31,-2.29,;-.02,-1.52,;-1.35,-2.29,;2.64,-1.52,;3.97,-2.29,;5.3,-1.52,;9.15,-2.78,;10.23,-1.68,;8.29,-4.04,;9.25,-5.25,;8.69,-6.68,;7.5,-7.64,;8.94,-8.2,)| | ||
Structure |