Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50122531 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_145593 (CHEMBL749738) | ||
IC50 | 130±n/a nM | ||
Citation | Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
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BDBM50122531 | |||
n/a | |||
Name | BDBM50122531 | ||
Synonyms: | 20-azapentacyclo[7.6.5.02,7.010,15.016,20]icosa-2(7),3,5,12,14-pentaene-4,13-diol | ||
Type | Small organic molecule | ||
Emp. Form. | C19H21NO2 | ||
Mol. Mass. | 295.3755 | ||
SMILES | Oc1ccc2C[C@H]3[C@@H]4CCC(=O)C=C4[C@@H]([C@@H]4CCCN34)c2c1 |wU:6.20,14.14,7.13,15.21,c:12,TLB:8:7:19.15:20.4.5,21:20:19.15:13.7,THB:16:15:13.7:20.4.5,3:4:19.15:13.7,18:19:13.7:20.4.5,(-.13,-2.89,;1.2,-3.66,;1.2,-5.2,;2.54,-5.97,;3.85,-5.2,;5.19,-5.97,;6.74,-5.97,;6.52,-2.12,;7.85,-1.35,;7.85,.2,;6.52,.97,;6.5,2.51,;5.19,.2,;5.19,-1.35,;5.19,-2.89,;9.37,-4.45,;10.65,-5.31,;10.25,-6.78,;8.71,-6.85,;8.17,-5.42,;3.85,-3.66,;2.54,-2.89,)| | ||
Structure |