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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Kappa-type opioid receptor | ||
| Ligand | BDBM50122533 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_145111 (CHEMBL751994) | ||
| IC50 | >10000±n/a nM | ||
| Citation |  Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Kappa-type opioid receptor | |||
| Name: | Kappa-type opioid receptor | ||
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 42648.76 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41145 | ||
| Residue: | 380 | ||
| Sequence: |
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| BDBM50122533 | |||
| n/a | |||
| Name | BDBM50122533 | ||
| Synonyms: | 17-cyclopropylmethyl-16-methyl-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaene | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H25N | ||
| Mol. Mass. | 291.4299 | ||
| SMILES | C[C@@H]1[C@@H]2C3=CC=CC[C@H]3[C@H](Cc3ccccc23)N1CC1CC1 |wU:2.2,9.19,8.7,1.0,c:5,t:3,TLB:0:1:3.8:16.10.11,15:16:17.1:3.8,THB:7:8:17.1:16.10.11,12:11:17.1:3.8,18:17:3.8:16.10.11,(9.27,-1.06,;7.84,-1.61,;4.09,-.36,;4.08,1.18,;4.08,2.72,;5.41,3.49,;6.74,2.73,;6.75,1.18,;5.41,.41,;5.63,-3.46,;4.09,-3.46,;2.76,-2.69,;1.42,-3.46,;.09,-2.69,;.09,-1.14,;1.42,-.37,;2.76,-1.14,;7.08,-2.95,;8.06,-4.11,;7.54,-5.56,;6.35,-6.56,;7.8,-7.09,)| | ||
| Structure | 
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