Reaction Details | |||
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Target | Kappa-type opioid receptor | ||
Ligand | BDBM50122542 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_145111 (CHEMBL751994) | ||
IC50 | 204±n/a nM | ||
Citation | Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Kappa-type opioid receptor | |||
Name: | Kappa-type opioid receptor | ||
Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 42648.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41145 | ||
Residue: | 380 | ||
Sequence: |
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BDBM50122542 | |||
n/a | |||
Name | BDBM50122542 | ||
Synonyms: | 17-cyclopropylmethyl-16-methyl-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaene-4,13-diol | ||
Type | Small organic molecule | ||
Emp. Form. | C21H25NO2 | ||
Mol. Mass. | 323.4287 | ||
SMILES | C[C@@H]1[C@@H]2C3=CC(=O)CC[C@H]3[C@H](Cc3ccc(O)cc23)N1CC1CC1 |wU:2.2,10.21,9.8,1.0,t:3,TLB:0:1:3.9:18.12.11,17:18:19.1:3.9,THB:13:12:19.1:3.9,20:19:3.9:18.12.11,8:9:19.1:18.12.11,(9.83,-1.73,;8.73,-2.83,;4.91,-1.57,;4.91,-.02,;4.91,1.53,;6.24,2.3,;6.24,3.84,;7.57,1.53,;7.57,-.02,;6.24,-.79,;6.45,-4.65,;4.91,-4.65,;3.58,-3.88,;2.25,-4.65,;.91,-3.88,;.91,-2.34,;-.44,-1.55,;2.25,-1.57,;3.58,-2.34,;7.89,-4.11,;8.85,-5.3,;8.29,-6.75,;7.09,-7.7,;8.52,-8.27,)| | ||
Structure |