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TargetCytochrome P450 2D26
LigandBDBM50122615
Substrate/Competitorn/a
Meas. Tech.ChEMBL_51710 (CHEMBL665725)
IC50 66400±n/a nM
Citation Venhorst, Jter Laak, AMCommandeur, JNFunae, YHiroi, TVermeulen, NP Homology modeling of rat and human cytochrome P450 2D (CYP2D) isoforms and computational rationalization of experimental ligand-binding specificities. J Med Chem46:74-86 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cytochrome P450 2D26
Name:Cytochrome P450 2D26
Synonyms:CP2DQ_RAT | CYPIID26 | Cyp2d-26 | Cyp2d2 | Cyp2d26 | Cytochrome P450 2D2 | Cytochrome P450 2D26 | Debrisoquine 4-hydroxylase | P450-CMF2 | P450-DB2
Type:PROTEIN
Mol. Mass.:56689.75
Organism:Rattus norvegicus
Description:ChEMBL_51710
Residue:500
Sequence:
MGLLIGDDLWAVVIFTAIFLLLVDLVHRHKFWTAHYPPGPVPLPGLGNLLQVDFENMPYS
LYKLRSRYGDVFSLQIAWKPVVVINGLKAVRELLVTYGEDTADRPLLPIYNHLGYGNKSK
GVVLAPYGPEWREQRRFSVSTLRDFGVGKKSLEQWVTEEAGHLCDTFAKEAEHPFNPSIL
LSKAVSNVIASLVYARRFEYEDPFFNRMLKTLKESFGEDTGFMAEVLNAIPILLQIPGLP
GKVFPKLNSFIALVDKMLIEHKKSWDPAQPPRDMTDAFLAEMQKAKGNPESSFNDENLRL
VVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHEEIDEVIGQVRRPEMADQARMPFTN
AVIHEVQRFADIVPTNIPHMTSRDIKFQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHP
EHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVLAGRPRPST
HGVYALPVTPQPYQLCAVAR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50122615
n/a
NameBDBM50122615
Synonyms:CHEMBL2373353 | Dodecahydro-7,14-methano-dipyrido[1,2-a;1',2'-e][1,5]diazocine
TypeSmall organic molecule
Emp. Form.C15H26N2
Mol. Mass.234.3803
SMILES[H][C@]12CN3CCCCC3[C@]([H])(CN3CCCCC13)C2
Structure
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