Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50128084 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_146316 (CHEMBL758863) |
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Ki | 9.1±n/a nM |
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Citation | Schlechtingen, G; DeHaven, RN; Daubert, JD; Cassel, JA; Chung, NN; Schiller, PW; Taulane, JP; Goodman, M Structure-activity relationships of dynorphin a analogues modified in the address sequence. J Med Chem46:2104-9 (2003) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50128084 |
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n/a |
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Name | BDBM50128084 |
Synonyms: | CHEMBL63188 | Tyr-Gly-Gly-Phe-Leu-Arg-OH |
Type | Small organic molecule |
Emp. Form. | C34H49N9O8 |
Mol. Mass. | 711.8084 |
SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
Structure |
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