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TargetCannabinoid receptor 1
LigandBDBM50128094
Substrate/Competitorn/a
Meas. Tech.ChEMBL_46450 (CHEMBL657898)
Ki 3700±n/a nM
Citation Wrobleski, STChen, PHynes, JLin, SNorris, DJPandit, CRSpergel, SWu, HTokarski, JSChen, XGillooly, KMKiener, PAMcIntyre, KWPatil-Koota, VShuster, DJTurk, LAYang, GLeftheris, K Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties. J Med Chem46:2110-6 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1
Name:Cannabinoid receptor 1
Synonyms:CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52868.96
Organism:Homo sapiens (Human)
Description:P21554
Residue:472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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  Blast E-value cutoff:
BDBM50128094
n/a
NameBDBM50128094
Synonyms:6-Methoxy-2-(2-methoxy-benzyl)-5-(2-morpholin-4-yl-ethyl)-2,5-dihydro-pyrido[4,3-b]indol-1-one | CHEMBL63561
TypeSmall organic molecule
Emp. Form.C26H29N3O4
Mol. Mass.447.5262
SMILESCOc1ccccc1Cn1ccc2n(CCN3CCOCC3)c3c(OC)cccc3c2c1=O
Structure
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