| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
|---|
| Ligand | BDBM50128112 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_203193 (CHEMBL804438) |
|---|
| Ki | 9.65±n/a nM |
|---|
| Citation |  Berardi, F; Loiodice, F; Fracchiolla, G; Colabufo, NA; Perrone, R; Tortorella, V Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites. J Med Chem46:2117-24 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
|---|
| Name: | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
|---|
| Synonyms: | EBP | EBP_CAVPO |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 26684.52 |
|---|
| Organism: | Cavia porcellus |
|---|
| Description: | ChEMBL_203193 |
|---|
| Residue: | 229 |
|---|
| Sequence: | MATTSTGPLHPYWPRHLRLDHFVPNDLSAWYIVTVLFTVFGALVVTMWLLSSRASVVPLG
TWRRLSVCWFAVCAFVHLVIEGWFVLYQKAILGDQAFLSQLWKEYAKGDSRYIIEDNFII
CMESITVVLWGPLSLWAVIAFLRQHPSRYVLQFVISLGQIYGDLLYFLTEYRDGFQHGEM
GHPIYFWFYFFFMNVLWLVIPGVLFFDSVKQFYGAQNALDTKVMKSKGK
|
|
|
|---|
| BDBM50128112 |
|---|
| n/a |
|---|
| Name | BDBM50128112 |
|---|
| Synonyms: | 1-[3-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidine; hydrochloride | CHEMBL540289 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H22ClNO |
|---|
| Mol. Mass. | 267.794 |
|---|
| SMILES | CC1CCN(CCCOc2ccc(Cl)cc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
