| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50128103 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201912 (CHEMBL808202) |
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| Ki | 2.21±n/a nM |
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| Citation |  Berardi, F; Loiodice, F; Fracchiolla, G; Colabufo, NA; Perrone, R; Tortorella, V Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites. J Med Chem46:2117-24 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50128103 |
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| n/a |
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| Name | BDBM50128103 |
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| Synonyms: | 1-[3-(4-Chloro-phenoxy)-1-methyl-propyl]-4-methyl-piperidine; hydrochloride | CHEMBL545691 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24ClNO |
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| Mol. Mass. | 281.821 |
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| SMILES | C[C@H](CCOc1ccc(Cl)cc1)N1CCC(C)CC1 |
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| Structure | 
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