| Reaction Details |
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 | Report a problem with these data |
| Target | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
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| Ligand | BDBM50128109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_203193 (CHEMBL804438) |
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| Ki | 12±n/a nM |
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| Citation |  Berardi, F; Loiodice, F; Fracchiolla, G; Colabufo, NA; Perrone, R; Tortorella, V Synthesis of chiral 1-[omega-(4-chlorophenoxy)alkyl]-4-methylpiperidines and their biological evaluation at sigma1, sigma2, and sterol delta8-delta7 isomerase sites. J Med Chem46:2117-24 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
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| Name: | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase |
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| Synonyms: | EBP | EBP_CAVPO |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26684.52 |
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| Organism: | Cavia porcellus |
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| Description: | ChEMBL_203193 |
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| Residue: | 229 |
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| Sequence: | MATTSTGPLHPYWPRHLRLDHFVPNDLSAWYIVTVLFTVFGALVVTMWLLSSRASVVPLG
TWRRLSVCWFAVCAFVHLVIEGWFVLYQKAILGDQAFLSQLWKEYAKGDSRYIIEDNFII
CMESITVVLWGPLSLWAVIAFLRQHPSRYVLQFVISLGQIYGDLLYFLTEYRDGFQHGEM
GHPIYFWFYFFFMNVLWLVIPGVLFFDSVKQFYGAQNALDTKVMKSKGK
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| BDBM50128109 |
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| n/a |
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| Name | BDBM50128109 |
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| Synonyms: | 1-[3-(4-Chloro-phenoxy)-butyl]-4-methyl-piperidine; hydrochloride | CHEMBL543581 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H24ClNO |
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| Mol. Mass. | 281.821 |
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| SMILES | C[C@@H](CCN1CCC(C)CC1)Oc1ccc(Cl)cc1 |
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| Structure | 
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