| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
|---|
| Ligand | BDBM50129680 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_98401 (CHEMBL881814) |
|---|
| Ki | 4880±n/a nM |
|---|
| Citation |  Grembecka, J; Mucha, A; Cierpicki, T; Kafarski, P The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity. J Med Chem46:2641-55 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytosol aminopeptidase |
|---|
| Name: | Cytosol aminopeptidase |
|---|
| Synonyms: | AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56171.75 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507539 |
|---|
| Residue: | 519 |
|---|
| Sequence: | MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD
KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN
IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS
GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI
EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD
LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
|
|
|
|---|
| BDBM50129680 |
|---|
| n/a |
|---|
| Name | BDBM50129680 |
|---|
| Synonyms: | CHEMBL423870 | {[hydroxy(1-hydroxy-3-methylbutyl)phosphoryl]amino}acetic acid; dilithium salt |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H14NO5P |
|---|
| Mol. Mass. | 223.1646 |
|---|
| SMILES | CC(C)CC(O)P([O-])(=O)NCC([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
