Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 6 |
---|
Ligand | BDBM50130264 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_3664 (CHEMBL620800) |
---|
Ki | 1.4±n/a nM |
---|
Citation | Glennon, RA Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). J Med Chem46:2795-812 (2003) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
5-hydroxytryptamine receptor 6 |
---|
Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
|
|
|
BDBM50130264 |
---|
n/a |
---|
Name | BDBM50130264 |
Synonyms: | 5-(1,4-diazepan-1-yl)-2-(4-fluorophenylsulfonyl)-N-methylbenzenamine | CHEMBL95136 | [5-[1,4]Diazepan-1-yl-2-(4-fluoro-benzenesulfonyl)-phenyl]-methyl-amine |
Type | Small organic molecule |
Emp. Form. | C18H22FN3O2S |
Mol. Mass. | 363.45 |
SMILES | CNc1cc(ccc1S(=O)(=O)c1ccc(F)cc1)N1CCCNCC1 |
Structure |
|