| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NH(3)-dependent NAD(+) synthetase |
|---|
| Ligand | BDBM50130797 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_141613 (CHEMBL747929) |
|---|
| IC50 | >200000±n/a nM |
|---|
| Citation |  Velu, SE; Cristofoli, WA; Garcia, GJ; Brouillette, CG; Pierson, MC; Luan, CH; DeLucas, LJ; Brouillette, WJ Tethered dimers as NAD synthetase inhibitors with antibacterial activity. J Med Chem46:3371-81 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NH(3)-dependent NAD(+) synthetase |
|---|
| Name: | NH(3)-dependent NAD(+) synthetase |
|---|
| Synonyms: | GSP38 | General stress protein 38 | NADE_BACSU | Spore outgrowth factor B | Sporulation protein outB | nadE | outB |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30386.77 |
|---|
| Organism: | Bacillus subtilis |
|---|
| Description: | ChEMBL_141613 |
|---|
| Residue: | 272 |
|---|
| Sequence: | MSMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQ
LAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQ
QETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLL
PLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKE
VSAKVSEALEKRYSMTEHKRQVPASMFDDWWK
|
|
|
|---|
| BDBM50130797 |
|---|
| n/a |
|---|
| Name | BDBM50130797 |
|---|
| Synonyms: | 3-[8-(5-Hydroxy-indol-1-yl)-octyloxycarbonyl]-pyridinium; iodide | CHEMBL114270 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H27N2O3 |
|---|
| Mol. Mass. | 367.4608 |
|---|
| SMILES | Oc1ccc2n(CCCCCCCCOC(=O)c3ccc[nH+]c3)ccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
