| Reaction Details |
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 | Report a problem with these data |
| Target | NH(3)-dependent NAD(+) synthetase |
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| Ligand | BDBM50130820 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_141613 (CHEMBL747929) |
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| IC50 | 44000±n/a nM |
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| Citation |  Velu, SE; Cristofoli, WA; Garcia, GJ; Brouillette, CG; Pierson, MC; Luan, CH; DeLucas, LJ; Brouillette, WJ Tethered dimers as NAD synthetase inhibitors with antibacterial activity. J Med Chem46:3371-81 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NH(3)-dependent NAD(+) synthetase |
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| Name: | NH(3)-dependent NAD(+) synthetase |
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| Synonyms: | GSP38 | General stress protein 38 | NADE_BACSU | Spore outgrowth factor B | Sporulation protein outB | nadE | outB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30386.77 |
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| Organism: | Bacillus subtilis |
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| Description: | ChEMBL_141613 |
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| Residue: | 272 |
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| Sequence: | MSMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQ
LAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQ
QETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLL
PLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKE
VSAKVSEALEKRYSMTEHKRQVPASMFDDWWK
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| BDBM50130820 |
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| n/a |
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| Name | BDBM50130820 |
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| Synonyms: | 4-[8-(2-Methoxycarbonyl-indol-1-yl)-octyloxycarbonyl]-1-methyl-pyridinium; iodide | CHEMBL113836 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31N2O4 |
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| Mol. Mass. | 423.5241 |
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| SMILES | COC(=O)c1cc2ccccc2n1CCCCCCCCOC(=O)c1cc[n+](C)cc1 |
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| Structure | 
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