| Reaction Details |
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 | Report a problem with these data |
| Target | MO15-related protein kinase Pfmrk |
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| Ligand | BDBM5718 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_52684 (CHEMBL666139) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Woodard, CL; Li, Z; Kathcart, AK; Terrell, J; Gerena, L; Lopez-Sanchez, M; Kyle, DE; Bhattacharjee, AK; Nichols, DA; Ellis, W; Prigge, ST; Geyer, JA; Waters, NC Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases. J Med Chem46:3877-82 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| MO15-related protein kinase Pfmrk |
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| Name: | MO15-related protein kinase Pfmrk |
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| Synonyms: | Protein kinase Pfmrk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37992.30 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_640752 |
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| Residue: | 324 |
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| Sequence: | MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLL
REIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQI
LNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLN
LTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFL
LGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAED
AMKHRYFFNDPLPCDISQLPFNDL
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| BDBM5718 |
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| n/a |
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| Name | BDBM5718 |
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| Synonyms: | 2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(benzylamino)-9-methyl-9H-purin-2-yl]amino}ethan-1-ol | 2-{[6-(benzylamino)-9-methyl-9H-purin-2-yl]amino}ethanol | 6-(benzylamino)-2-[(2-hydroxyethyl)amino]-9-methylpurine | CHEMBL280074 | Olomoucine | purine deriv. 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N6O |
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| Mol. Mass. | 298.343 |
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| SMILES | Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 |
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| Structure | 
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