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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50133226 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_148855 (CHEMBL756651) | ||
| Ki | 0.19±n/a nM | ||
| Citation |  Schütz, J; Spetea, M; Koch, M; Aceto, MD; Harris, LS; Coop, A; Schmidhammer, H Synthesis and biological evaluation of 14-alkoxymorphinans. 20. 14-phenylpropoxymetopon: an extremely powerful analgesic. J Med Chem46:4182-7 (2003) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44503.11 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. | ||
| Residue: | 398 | ||
| Sequence: |
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| BDBM50133226 | |||
| n/a | |||
| Name | BDBM50133226 | ||
| Synonyms: | 15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11,16-tetraene | CHEMBL133836 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H33NO2 | ||
| Mol. Mass. | 379.535 | ||
| SMILES | CCC[C@H](C)C1C[C@]23C=C[C@]1(OC)[C@@H]1Oc4cccc5C[C@H]2N(C)CC[C@@]31c45 |wU:21.23,wD:13.14,26.30,7.7,10.11,3.3,c:8,(-6.72,-4.49,;-6.72,-3.27,;-7.83,-2.27,;-7.83,-.96,;-9.4,-.96,;-6.2,-.93,;-5.43,-2.25,;-3.89,-2.25,;-4.15,-.92,;-5.15,-.92,;-5.48,.41,;-6.13,1.56,;-7.77,1.56,;-3.91,.41,;-2.42,1.4,;-.81,.42,;.75,.42,;1.52,-.93,;.75,-2.25,;-.81,-2.25,;-1.6,-3.58,;-3.15,-3.58,;-3.75,-4.85,;-3.75,-6.7,;-2.31,-4.85,;-2.31,-2.04,;-3.17,-.92,;-1.6,-.92,)| | ||
| Structure | 
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