| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50122851 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_148089 (CHEMBL751571) |
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| Ki | 4.6±n/a nM |
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| Citation |  Black, SL; Jales, AR; Brandt, W; Lewis, JW; Husbands, SM The role of the side chain in determining relative delta- and kappa-affinity in C5'-substituted analogues of naltrindole. J Med Chem46:314-7 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50122851 |
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| n/a |
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| Name | BDBM50122851 |
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| Synonyms: | 7N-(4-methoxybenzyl)-22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-7-carboxamide | CHEMBL431060 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H35N3O5 |
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| Mol. Mass. | 577.6695 |
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| SMILES | COc1ccc(CNC(=O)c2ccc3[nH]c4[C@@H]5Oc6c7c(CC8N(CC9CC9)CC[C@@]57[C@@]8(O)Cc4c3c2)ccc6O)cc1 |TLB:18:19:31:23.29.28,37:20:31:23.29.28| |
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| Structure | 
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