| Reaction Details |
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 | Report a problem with these data |
| Target | Malate dehydrogenase, cytoplasmic |
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| Ligand | BDBM25817 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104019 (CHEMBL709628) |
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| IC50 | >400000±n/a nM |
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| Citation |  Seidler, J; McGovern, SL; Doman, TN; Shoichet, BK Identification and prediction of promiscuous aggregating inhibitors among known drugs. J Med Chem46:4477-86 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Malate dehydrogenase, cytoplasmic |
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| Name: | Malate dehydrogenase, cytoplasmic |
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| Synonyms: | Cytosolic malate dehydrogenase | MDH1 | MDHA | MDHC_HUMAN | Malate dehydrogenase cytoplasmic | Malate dehydrogenase, cytoplasmic |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36427.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1456624 |
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| Residue: | 334 |
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| Sequence: | MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA
KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN
VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL
SSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFV
EGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
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| BDBM25817 |
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| n/a |
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| Name | BDBM25817 |
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| Synonyms: | 2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol | CHEMBL106 | Diflucan | Fluconazole | Fluconazole (f) | Fungata | Triflucan | US10221160, Fluconazole | US11247981, Example Fluconazole | US9138393, Fluconazole | US9144538, Fluconazole | US9221791, Fluconazole | US9556143, Fluconazole | cid_3365 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12F2N6O |
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| Mol. Mass. | 306.2708 |
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| SMILES | OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F |
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| Structure | 
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