| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM31774 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_40567 (CHEMBL651415) |
|---|
| IC50 | 20000±n/a nM |
|---|
| Citation |  Seidler, J; McGovern, SL; Doman, TN; Shoichet, BK Identification and prediction of promiscuous aggregating inhibitors among known drugs. J Med Chem46:4477-86 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
|---|
| Type: | Protien |
|---|
| Mol. Mass.: | 41561.62 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P00811 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
|
|
|
|---|
| BDBM31774 |
|---|
| n/a |
|---|
| Name | BDBM31774 |
|---|
| Synonyms: | CHEMBL104 | Canesten | Clotrimazole | Lotrimin | Mycelex | US9138393, Clotrimazole | cid_2812 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H17ClN2 |
|---|
| Mol. Mass. | 344.837 |
|---|
| SMILES | Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 |
|---|
| Structure | 
|
|---|
Search and Browse
