| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM31773 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_40567 (CHEMBL651415) |
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| IC50 | 25000±n/a nM |
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| Citation |  Seidler, J; McGovern, SL; Doman, TN; Shoichet, BK Identification and prediction of promiscuous aggregating inhibitors among known drugs. J Med Chem46:4477-86 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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| BDBM31773 |
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| n/a |
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| Name | BDBM31773 |
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| Synonyms: | ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pevaryl | cid_68589 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15Cl3N2O |
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| Mol. Mass. | 381.684 |
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| SMILES | Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 |
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| Structure | 
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