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TargetConstitutive androstane receptor
LigandBDBM8885
Substrate/Competitorn/a
Meas. Tech.ChEMBL_48049
IC50 30000±n/a nM
Citation Jyrkkärinne JMäkinen JGynther JSavolainen HPoso AHonkakoski P Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. J Med Chem 46:4687-95 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Constitutive androstane receptor
Name:Constitutive androstane receptor
Synonyms:CAR | Nr1i3 | Nuclear receptor subfamily 1 group I member 3 | Orphan nuclear receptor MB67
Type:PROTEIN
Mol. Mass.:40922.30
Organism:Mus musculus
Description:ChEMBL_48051
Residue:358
Sequence:
MTAMLTLETMASEEEYGPRNCVVCGDRATGYHFHALTCEGCKGFFRRTVSKTIGPICPFA
GRCEVSKAQRRHCPACRLQKCLNVGMRKDMILSAEALALRRARQAQRRAEKASLQLNQQQ
KELVQILLGAHTRHVGPMFDQFVQFKPPAYLFMHHRPFQPRGPVLPLLTHFADINTFMVQ
QIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHISLNTTFCLQTENFFCGPLCYKMEDAV
HAGFQYEFLESILHFHKNLKGLHLQEPEYVLMAATALFSPDRPGVTQREEIDQLQEEMAL
ILNNHIMEQQSRLQSRFLYAKLMGLLADLRSINNAYSYELQRLEELSAMTPLLGEICS
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  Blast E-value cutoff:
BDBM8885
n/a
NameBDBM8885
Synonyms:(1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one | 17beta-Hydroxyandrost-4-en-3-one | Testosterone | Testosterone, 1 | US9682960, Testosterone
TypeSteroid
Emp. Form.C19H28O2
Mol. Mass.288.4244
SMILES[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |r,t:18|
Structure
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