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TargetDipeptidyl peptidase 2
LigandBDBM50118946
Substrate/Competitorn/a
Meas. Tech.ChEMBL_53369 (CHEMBL666615)
Ki 1430±n/a nM
Citation Senten, KVan der Veken, PDe Meester, ILambeir, AMScharpé, SHaemers, AAugustyns, K Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases. J Med Chem46:5005-14 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dipeptidyl peptidase 2
Name:Dipeptidyl peptidase 2
Synonyms:DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase
Type:Protein
Mol. Mass.:54339.29
Organism:Homo sapiens (Human)
Description:Q9UHL4
Residue:492
Sequence:
MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
QPALRGGPRLSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50118946
n/a
NameBDBM50118946
Synonyms:(S)-2-Amino-1-pyrrolidin-1-yl-propane-1-thione | CHEMBL97483
TypeSmall organic molecule
Emp. Form.C7H14N2S
Mol. Mass.158.264
SMILESC[C@H](N)C(=S)N1CCCC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: