| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase |
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| Ligand | BDBM50135767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_87394 (CHEMBL691509) |
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| IC50 | 0.8±n/a nM |
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| Citation |  Miller, TA; Witter, DJ; Belvedere, S Histone deacetylase inhibitors. J Med Chem46:5097-116 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase |
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| Name: | Histone deacetylase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50433.01 |
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| Organism: | Cryptosporidium parvum |
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| Description: | ChEMBL_79057 |
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| Residue: | 444 |
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| Sequence: | MAKRVSYFYDGDIGSYYYGPGHPMKPQRIRMAHNLILSYDLYKHMEIYKPHKSPQSELVY
FHEEDYINFLSSINPDNSKDFGLQLKRFNLGETTDCPVFDGLFEFQQICAGGSIDGAYKL
NNEQSDICINWSGGLHHAKRSEASGFCYINDIVLGILELLKYHARVMYIDIDVHHGDGVE
EAFYLSHRVLTVSFHKFGEFFPGTGDITDIGVAQGKYYSVNVPLNDGIDDDSFLSLFKPI
ISKCIEVYRPGAIVLQCGADSVRGDRLGRFNLSIKGHAECVEFCKKFNIPLLILGGGGYT
IRNVARTWAYETATILDRTDLISDNIPLNDYYDYFAPDFKLHIPPLNLPNMNSPEHLEKI
KAKVIDNLRYLEHAPGVEFAYVPSDFFDREASNLQKQEDEEREEELSSWQGGGRAAGSTE
SQGNHNEKPKSSRKLQKEHASEFY
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| BDBM50135767 |
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| n/a |
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| Name | BDBM50135767 |
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| Synonyms: | 6-[(6S,9S,12S,14aR)-6-sec-Butyl-9-(1-methoxy-1H-indol-3-ylmethyl)-5,8,11,14-tetraoxo-tetradecahydro-4a,7,10,13-tetraaza-benzocyclododecen-12-yl]-hexanoic acid methyl ester | CHEMBL356177 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H47N5O7 |
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| Mol. Mass. | 625.7556 |
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| SMILES | CCC(C)[C@@H]1NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC(=O)[C@H](CCCCCC(=O)OC)NC(=O)[C@H]2CCCCN2C1=O |
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| Structure | 
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